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Rubor et tumor cum calore et dolore
    Differential Diagnosis[Top] [Nav]
acute inflammation
    Discussion -- not available online[Top] [Nav]
    Errata in printed version[Top] [Nav]
       *[footnote 2] The book was omitted from the index.
       *[footnote 3] The last page of the article is 322, not 323.
    Update Comments[Top] [Nav]
  • The Ebers papyrus (1550 B.C.) describes 2 of the 4 cardinal signs of inflammation:
    When you examine an irregular wound... and that wound is inflamed... [there is] a concentration of heat; the lips of that wound are reddened and that man is hot in consequence... then you must make cooling substances for him to draw the heat out... leaves of the willow.
    Interestingly, willow leaves contain salicylic acid, which is an effective anti-inflammatory, but has an unpleasant taste and upsets the stomach. These shortcomings left the door open for acetylsalicylic acid -- aspirin. [101]
    Footnotes in Print Edition[Top] [Nav]
    (1) The Healing Hand: Man and Wound in the Ancient World.
  Majno G. Cambridge, MA: Harvard, 1975: 370-374, 412-413.   Amazon.com
    (2) History of Medicine. 4th ed.
  Garrison FH. Philadelphia: Saunders, 1929: 107-109.   Amazon.com
    (3) Disturbance of function (functio laesa): the legendary fifth cardinal sign of inflammation, added by Galen to the four cardinal signs of Celsus.
  Rather LJ.   Bull N Y Acad Med 1971 Mar;47(3):303-22.  Pubmed  Similars
    New References[Top] [Nav]
    101.One hundred years of aspirin.
  Jack DB.   Lancet 1997 Aug 9;350(9075):437-9.  Pubmed  Similars
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    AB BL DI EA EN EX EY FA GE GI GU HD HE IM LU MO MU NC NE NO SK TH VI WI
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    ©1986-2000 John Sotos, MD. All rights reserved.  Last updated 16:34 PDT on July 4, 2000.[Top]

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