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Muscular pain 5 to 10 minutes after starting exercise | ||
| Differential Diagnosis | [Top] [Nav] | |
McArdle disease (myophosphorylase deficiency) | ||
| Discussion -- not available online | [Top] [Nav] | |
| Erratum in printed version | [Top] [Nav] |
| * | There is a disorder of glycogenolysis that produces lactate in the ischemic forearm test. See below. |
| Update Comments | [Top] [Nav] | |
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| Footnotes in Print Edition | [Top] [Nav] |
| (1a) | Myopathy in McArdle's syndrome. Improvement with a high-protein diet. Slonim AE, Goans PJ. N Engl J Med 1985 Feb 7;312(6):355-9. Pubmed Similars | |
| (1b) | McArdle's disease in the 1980s [editorial]. Layzer RB. N Engl J Med 1985 Feb 7;312(6):370-1. Pubmed Similars | |
| (2a) | McKusick 232600 = McArdle disease (autosomal recessive). | |
| (2b) | McKusick 153460 = McArdle disease (autosomal dominant). | |
| (3) | Handbook of Clinical Neurology. Vinken PJ, Bruyn GW. Amsterdam: North Holland: 1979;41:175-234 [chapter = Di Mauro S. Metabolic myopathies]. |
| New References | [Top] [Nav] |
| 101. | A standardized forearm ischemic exercise test. Munsat TL. Neurology 1970 Dec;20(12):1171-8. Pubmed Similars | |
| 102. | Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 36-1986. A 29-year-old woman with slowly progressive proximal-muscle weakness. N Engl J Med 1986 Sep 11;315(11):694-701. Pubmed Similars |
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| ©1986-2000 John Sotos, MD. All rights reserved. Last updated 16:34 PDT on July 4, 2000. | [Top] | |