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Pain in the angles of the jaw when chewing solid food
    Differential Diagnosis[Top] [Nav]
giant cell arteritis, primary systemic amyloidosis
    Discussion -- not available online[Top] [Nav]
    Update Comments[Top] [Nav]
  • Of 30 patients with temporal arteritis who had a positive temporal artery biopsy, 15 (= 50%) had jaw claudication. Of 68 patients with the syndrome who had a negative biopsy, 12 (= 18%) had jaw claudication. [101]
  • Of 95 patients with Takayasu disease in this series, 2 had jaw claudication. [102]
  • "The presence of jaw claudication usually indicates an underlying vasculitis -- commonly giant cell arteritis -- but jaw claudication can occur in other patterns of vasculitis, including polyarteritis, Churg-Strauss syndrome, and Wegener's granulomatosis, and also in amyloidosis." [103]
  • Jaw pain is a side effect of epoprostenol (prostacyclin), used in the treatment of pulmonary hypertension. [104]
  • Goldsmith has studied the omentum for 25 years in man and animals, and never seen atherosclerosis in the omental arteries. Neither have the many pathologists he has asked over the years. [105]
  • The internal thoracic artery "is nearly always free of atherosclerosis in situ. Coronary angiographers have practically given up injecting the internal thoracic artery to verify the presence or absence of atherosclerosis, since it rarely, if ever, exists." [106]
    Footnotes in Print Edition[Top] [Nav]
    (1a) Case 51-1981: Axillary arteritis [letter].
  Crowley JG.   N Engl J Med 1982 May 27;306(21):1297.  Pubmed  Similars
    (1b) Rare Diseases and Lesions.
  Bean WB. Springfield, IL: Thomas, 1967: 45.
    (1c) On the "pulseless disease" outside of Japan.
  Ask-Upmark E.   Acta Med Scand. 1954;149:161-178.
    (2) Giant cell arteritis: including temporal arteritis and polymyalgia rheumatica.
  Hamilton CR Jr, Shelley WM, et al.   Medicine (Baltimore) 1971 Jan;50(1):1-27.  Pubmed  Similars
    (3) Jaw claudication in primary systemic amyloidosis.
  Gertz MA, Kyle RA, et al.   Medicine (Baltimore) 1986 May;65(3):173-9.  Pubmed+Abstract  Similars
    (4) Respiratory tract symptoms as a clue to giant cell arteritis.
  Larson TS, Hall S, et al.   Ann Intern Med 1984 Nov;101(5):594-7.  Pubmed+Abstract  Similars
    New References[Top] [Nav]
Jaw claudication
    101.Presenting features and outcomes in patients undergoing temporal artery biopsy. A review of 98 patients.
  Chmelewski WL, McKnight KM, et al.   Arch Intern Med 1992 Aug;152(8):1690-5.  Pubmed+Abstract  Similars
    102.Patterns of symptoms and prognosis in occlusive thromboaortopathy (Takayasu's disease).
  Ishikawa K.   J Am Coll Cardiol 1986 Nov;8(5):1041-6.  Pubmed+Abstract  Similars
    103.Update on systemic necrotizing vasculitis [see comments].
  Conn DL.   Mayo Clin Proc 1989 May;64(5):535-43.  Pubmed+Abstract  Similars
    104.Pulmonary hypertension--beyond vasodilator therapy [editorial; comment].
  Fishman AP.   N Engl J Med 1998 Jan 29;338(5):321-2.  Pubmed  Similars
Other arteries resistant to atherosclerosis
    105.Lack of atherosclerosis in omental arteries [letter].
  Goldsmith HS.   Lancet 1990 Feb 17;335(8686):409.  Pubmed  Similars
    106.The mysterious, internal thoracic artery [editorial] [see comments].
  Conti CR.   Clin Cardiol 1991 Jan;14(1):3-4.  Pubmed  Similars
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    ©1986-2000 John Sotos, MD. All rights reserved.  Last updated 16:34 PDT on July 4, 2000.[Top]

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